Standard narcotic analgesics in the Russian troops

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Standard narcotic analgesics in the Russian troops


Introduction


The SVO has raised interest in military medicine in the Russian Federation. And what is the situation with standard narcotic drugs in the military?



What are the trends, problems, prospects?

We will try to answer this question in as much detail as possible.

The article provides a review of standard narcotic analgesics in prehospital care.

The legal component of the issue


Here it is necessary to immediately make a remark that such a concept as "narcotic analgesic" is somewhat conditional. This is a legal and legislative relation of an analgesic to one of the groups of "narcotic drugs, psychotropic substances and their precursors subject to control in the Russian Federation" at the current moment in time.

The same analgesic at different times, according to the legislative base of the Russian Federation "On narcotic drugs and psychotropic substances", could be in different groups. That is, the same drug, having constant properties, according to the state register of drugs, could change the group several times over 10 years and, accordingly, the requirements for circulation and storage.

A drug can change its group within one legislative framework, the Federal legislative framework itself changes periodically, requirements within ministries and departments can change. And in all this diversity of laws, by-laws, orders, there is military and civilian medicine.

The authors deliberately do not provide the legislative framework itself in the article, as it is updated periodically.

Modern history of the issue. Liberal and Conservative approaches


In fact, two approaches can be distinguished to the storage, accounting and use of narcotic drugs in the military: liberal and conservative.

Let's look at them below.

1. Liberal


Issue of standard analgesics to all personnel. After use or misuse - replenishment.
Extended medical indications for use.

Simplified write-off, minimum reports or issuance and write-off by the notorious "direct expense". What this "accounting" system can lead to is well demonstrated in the film based on the stories of M.A. Bulgakov - "Morphine".

For example, in the 2000s in the Russian Federation there was a simplified circulation of such a drug as butorphanol. At one point, this drug was practically freely available in Russia and Ukraine. And during the same period in the Russian Federation, in the military link, they tried to replace promedol with butorphanol. The short but eventful period of butorphanol as a standard analgesic will be described below.

2. Conservative


The absence of standard narcotic analgesics in the individual first aid kits of military personnel. But the presence of these drugs in the kits of orderlies and medical instructors.

In the US Army, similar methods were used during the conflict in Afghanistan and Iraq. Where a medical helicopter would arrive 15 minutes after a soldier was wounded. The analgesic, when administered intramuscularly, according to its pharmacological properties, would only begin to act. In general, the configuration options for the individual first aid kit "IFAK" at that time are a subject for discussion.

In the US Army there is a restriction on the distribution of narcotic drugs in individual first aid kits. Considering the large number of "drug-positive" servicemen in the US, this step is entirely justified.

As is known, the army is an extension of society, and those who join the service, even in the USA, are far from being children of the aristocracy. But the US Army has a system of selection and career growth in the troops for privates and sergeants. And medicine is different in different military departments. This is all without counting the large number of military registration specialties in medicine. For example, the arsenal and algorithm of analgesia in the pre-hospital link of the TCCC (Tactical Combat Casualty Care) for US Ranger units from 2007 will be the envy of some anesthesiology and resuscitation departments in the Russian Federation in 2025.

Everything is relatively clear with the options for turnover and control, but what happened in the Russian Federation in the military sector from the 90s to the present in this area?

Search for the optimal drug for the Russian Armed Forces in the 90s - 2010s


In short, in the RF Armed Forces there was a constant struggle between a number of mutually exclusive demands.

1. Safe and injectable analgesic (as a rule, a narcotic drug is more effective).

2. Cheap drug (the drug is needed in large quantities, and that is why it had to be one). Storage at 110% of the drug and issue as needed. And no medical institution will use the drug after it has been stored somewhere responsibly for a couple of years.

This means that after 3–5 years the entire batch of the drug must be disposed of.

3. Minimum requirements for turnover and storage. Iron doors, alarms, accounting books, studies and permits. It is advisable to do without all this. And, of course, no refrigerators.

4. The main question at that time and at the same time the argument: why is this drug needed in such quantities in the RF Armed Forces if no one will use it?

It is clear that a painkiller can be either a ketorol tablet or such a well-known “cough remedy” as diacetylmorphine.

But the drug must be safe and effective, even in the hands of a soldier.

Promedol in combination with ketamine in subnarcotic doses met this requirement well. And we are omitting the rich experience of using amphetamine and its analogues in the armed forces of the USA, NATO countries and the USSR.

But, as we know, the law never sleeps. And the requirements for control and circulation of narcotic, potent and psychotropic drugs in the Russian Federation have been tightened, including for military medicine.

In the 90s and 2000s, the Russian Armed Forces were on the path of obtaining a standard narcotic analgesic that did not fall into the group of narcotic drugs.

The Russian Armed Forces searched for, but never found, a replacement for Promedol. At first it was Tramadol. Then it was Butorphanol, which successively moved from group B to group A and then to the group of narcotic drugs.

Both the drug distribution options and the drug itself could be different at different times and in different ministries and departments.

In some places, service analgesics were issued to all servicemen during combat missions. In some places, not to everyone, but only to medical workers. In some places, they were not issued to anyone.

They could issue “Promedol”, “Tramadol”, “Butorphanol”, and somewhere narcotic analgesics were kept in warehouses for the entire expiration date.

The initiation by the Prosecutor's Office and the Investigative Committee of the Russian Federation of licensing medical companies and medical stations as medical organizations in a number of areas of daily medical service activities has seriously limited such searches for the optimal drug. In particular, questions have arisen regarding the licensing of military units for the circulation, storage and use of narcotic drugs.

The decision, frankly speaking, is controversial and does not have a serious impact on the quality of medical care or its availability in the troops.

But the law is the law. After several years of courts and proceedings, everyone came to the conclusion that a medical company and a city hospital are not the same thing, and in a conventional motorized rifle regiment, medical activity is not a core activity. Around 2018, the military was left alone.

What is the current situation in the Russian Armed Forces with standard narcotic analgesics at the military level?


Currently, the Russian Armed Forces are receiving and using Nefopam (Akupan) en masse. Nefopam is produced in injection forms: ampoules and syringe tubes. It is slightly inferior in effectiveness to Promedol, but is not a narcotic drug. Of the minuses, Nefopam, like many other drugs, does not tolerate freezing well.

That is, now in the individual first aid kits of Russian military personnel there can be two types of standard analgesics in injectable form: narcotic - promedol, and non-narcotic - nefopam.

In June 2024, a manual for the RF Armed Forces was published: “Temporary Guidelines for the Use of Analgesics” - May 2024 (Fig. 1). The manual was created under the influence of the analgesia algorithm from the modern version of TCCC (Tactical Combat Casualty Care) (Fig. 2).
The TSSS analgesia algorithm was originally created for US Special Operations Forces servicemen. It is somewhat difficult to implement for an ordinary soldier or a medical instructor. The RF Armed Forces analgesia algorithm version can be called abbreviated and revised for a wider range of servicemen.

This guideline has added another narcotic analgesic for pre-hospital use in the RF Armed Forces – buprenorphine.

For quite a long time there has been a discussion about the use of the following drugs in the pre-hospital setting: ketamine, morphine, fentanyl.

These drugs have a number of restrictions for use in individual first aid kits.

Ketamine is not mass-produced in syringe tubes, and was not produced in the required dosage for single use at the pre-hospital stage.

Morphine is effective and safe only in the hands of a specialist, it has a large number of side effects that need to be noticed and prevented in time.

Fentanyl is more suitable for group paramedic placement or for work at the medical company stage. On the plus side, transdermal forms of this drug are produced in the Russian Federation, which can find their niche of application.

Due to the above restrictions, three drugs: ketamine, morphine, fentanyl - are used from the stage of qualified medical care.

One of the modern realities of the Russian Federation is that, as in the United States, there are a number of servicemen with a history of drug addiction in the Russian military. It is important to understand that this does not change anything. This category of patients has always received and continues to receive all types of medical care from the Ministry of Health. At the same time, for objective reasons, no one in the Ministry of Health is changing the requirements for accounting and turnover due to these patients.

Conclusions


A balanced approach to the accounting, competent distribution and expansion of the arsenal of standard analgesics in individual first aid kits, analgesics in group kits of medical orderlies and paramedics and in the entire pre-hospital link is desirable.
The search and research on the selection of new and effective narcotic and non-narcotic analgesics for the pre-hospital link continues. Priority is given to drugs that are already produced and used in the Russian Federation. And in general, for 3 years in this area, there is reason for cautious optimism.

The article is analytical in nature, does not contain propaganda for the use of psychoactive substances, all data was obtained from open sources.


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  1. +8
    24 January 2025 08: 20
    For prehospital care, I am a fan of the "it-cel sleep tube": etomidate, celocurine, intubation, of course with fentanyl and midazolam to maintain anesthesia.
    This is a prehospital care protocol used in France, especially during road accidents. Disadvantage: sometimes dangerous conditions require doctors trained in anesthesiology.
  2. +8
    24 January 2025 08: 55
    The problem with nefopam/tramadol is that they tend to cause vomiting, which can interfere with the subsequent anesthesia.
    As for buprenorphine, its agonist/antagonist effect may interfere with the use of morphine used in anesthesiology (need to increase the morphine dose and therefore possible effects on the patient's blood pressure).
    The ideal option is indeed titration of morphine.
    1. +5
      24 January 2025 11: 50
      Quote from: zorglub bulgroz
      The problem with nefopam/tramadol is that they tend to cause vomiting.

      A lot depends on the speed of intravenous administration. The lower it is, the lower the probability of side effects. I have not encountered vomiting with tramadol when administered intramuscularly.
      Quote from: zorglub bulgroz
      The ideal option is indeed titration of morphine

      Without a doubt.
      Quote from: zorglub bulgroz
      Regarding buprenorphine, its agonist/antagonist effect may interfere with the use of morphine

      Now here's where it gets interesting. Doesn't the action become potentiated?
      1. +4
        24 January 2025 12: 19
        Quote: FIR FIR
        Isn't there a potentiation of action?

        On the contrary, a decrease in the degree of analgesia is possible...
    2. +1
      26 January 2025 14: 06
      Quote from: zorglub bulgroz
      The problem with nefopam/tramadol is that they tend to cause vomiting, which can interfere with the subsequent anesthesia.

      The problem is solved quite simply, by parallel administration of ondansetron. Unfortunately, the level of training of self-help fighters is still close to zero. Not even all the medics of the units can boast of qualifications higher than the level of Takmed courses. Evacuation sometimes drags on for several days, and antibiotics of general action are absent from the first-aid kits of almost everyone. As a result, amputation or death.
      1. 0
        26 January 2025 16: 23
        This article has a fairly narrow topic.
        Part of the fight against complications is shown in the 2007 diagram.
  3. +5
    24 January 2025 10: 10
    wonderful! Over the last 50 years, a replacement for promedol has not been found? That's what they were like, the communists, they invented a miracle drug that has had no competitors in terms of effectiveness for so many years!!!
    1. +4
      24 January 2025 14: 02
      wonderful! Over the last 50 years, a replacement for promedol has not been found? That's what they were like, the communists, they invented a miracle drug that has had no competitors in terms of effectiveness for so many years!!!

      This miracle is the only one we use. It is weak, but it knocks out your breathing as well. In the world - morphine, but this is also not a solution.

      At the pre-hospital stage, I would generally leave only diclofenac, the effect is about the same as drugs, it does not depress breathing, it is freely available, it is easier to store and renew.
    2. +4
      24 January 2025 14: 26
      Quote: realist
      Over the past 50 years, a replacement for promedol has not been found

      In practice, synthetic variations of the sufentanil type are already used, which are thousands of times stronger than the same promedol. The whole question is in mass production and cost, and here the old-''good'' promedol-morphine have no competitors.
    3. +3
      24 January 2025 17: 55
      In principle, the reasons for Promedol’s relevance are described in detail above.
      This is a combination of qualities: safety, efficiency, PRICE!
  4. +9
    24 January 2025 13: 40
    The purely military-medical issue is being replaced by an "effective" fight against drug addiction and alcoholism. Even in school we were taught how and where to inject a painkiller from a tube on the battlefield. Now even potassium permanganate, which was previously used for bathing babies, is hard to buy. Drug addicts can allegedly use:
    1. +3
      24 January 2025 15: 08
      Exactly. And when you submit your urine for chemical-toxicological analysis, if you ate a bun with poppy seeds or drank Corvalol, you can be registered as a drug addict.
      In this case, the drug is eliminated from the body in a few days, while Corvalol lasts up to 45 days.
      1. +2
        24 January 2025 16: 24
        Quote: glory1974
        Exactly. And when you submit your urine for chemical-toxicological analysis, if you ate a bun with poppy seeds or drank Corvalol, you can be registered as a drug addict.
        In this case, the drug is eliminated from the body in a few days, while Corvalol lasts up to 45 days.

        Get ahead!
      2. +6
        24 January 2025 18: 06
        Quote: glory1974
        Exactly.

        Moreover, there is no maximum limit.
        However, in "democratic" Russia there are a couple of orders of magnitude more prohibitions for the average citizen than in the "totalitarian" USSR. On the Internet, they are seriously discussing whether it is possible to collect deadwood in the forest. I can confidently say - it is not possible. The snow has not melted yet and there is already a ban on visiting the forest due to the fire hazard. So, collecting deadwood, mushrooms, berries is illegal. belay
        1. -5
          29 January 2025 08: 40
          Quote: There was a mammoth
          However, in “democratic” Russia there are several orders of magnitude more prohibitions for the average citizen than in the “totalitarian” USSR.

          Only in the USSR they were somewhat harsher - the "Verkhnelarsovites" faced up to and including execution under the Criminal Code of 1926.
          And Navalny would have gotten a bullet in no time after the first rally, and those around him would have been studying the design of the pickaxe for the next 10 years...
          Quote: There was a mammoth
          There is a serious discussion on the Internet about whether it is possible to collect dead wood in the forest. I can confidently say - it is not possible.

          As in the USSR lol - only through the forestry
      3. 0
        1 February 2025 14: 43
        I don't believe about the bun. The seeds are baked, the substance will be destroyed.
    2. -3
      29 January 2025 08: 35
      Quote: There was a mammoth
      Now even potassium permanganate, which was previously used for bathing babies, is hard to buy. Drug addicts can allegedly use:

      Like acetone and acids, these are all precursors used in the production of drugs in large quantities.
      In Afghanistan, in the OKSVA, everything that was in the first aid kits with "dope" instantly went nowhere.
  5. +7
    24 January 2025 16: 22
    A balanced approach is desirable

    This is something that is completely, alas, absent in Russia. It is enough to recall the hysteria with Corvalol, or the ban on the use of effective analgesics and drugs for putting animals to sleep in veterinary medicine (to great regret, in 90% of cases the cause of death of an old dog is cancer and countless innocent dogs passed away in terrible agony because of this idiotic ban).
    What about medical/veterinary drugs?
    If there are any printing colleagues at VO, they will remember how a few years ago it was impossible to buy PRÄGO HART, a special compound, acrylic, judging by the smell, used to make equipment. The State Drug Committee suddenly decided that it could be distilled into drugs.
    I'm waiting for them to ban filling cars with gasoline and patching up torn soles with Moment.
    1. -1
      29 January 2025 08: 44
      Quote: Grossvater
      PRÄGO HART, a special compound, acrylic, judging by the smell, used to make equipment. The State Committee on Drugs suddenly decided that it could be distilled into drugs.

      After we distilled the liquid from the D-1 recuperators into booze during the conscription period in the artillery regiment and the division lowered the barrels, I believe that it is possible to distill ALL.
    2. 0
      14 March 2025 10: 59
      Quote: Grossvater
      ban on the use of effective analgesics and drugs for the euthanasia of animals in veterinary medicine

      I can’t resist sharing my personal experience:
      Once, standing in line with a dog at the State Veterinary Station for a vaccination, I heard screams, then a man came in carrying a cat with multiple injuries on a piece of plywood - a skinless tail, gnawed, half of a jaw was sticking out of the muzzle, everything between them was covered in blood, some entrails were sticking out, with each meow a pink bubble swelled from the middle. The cat owner loudly voiced the anamnesis - the cat fell into the hands of a "special" neighbor's child. The veterinarian could not stand it, took an ampoule out of the safe, injected it into the cat, and he fell silent. And then there was hysteria - the online drug database did not open, and the ampoule was already used up. The doctor explained that checks are frequent and they can put you in jail, that you first have to enter the data into the online form, and then, after the server approves from above, inject the drug into the animal.
      The former cat owner even said in the heat of the moment that "if he had known about the accounting problems, he would have finished off the cat with a shovel."
  6. +3
    27 January 2025 07: 13
    The topic is important, otherwise the losses from pain shock will be huge, I think it's time to switch to more radical drugs, capsules are needed and, as usual, Promedol, I liked the effect of this drug, it is possible to do the operation on a living person without anesthesia, which I did twice soldier