Hemostatic from mushrooms or shellfish? fashion sentence

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Hemostatic from mushrooms or shellfish? fashion sentence

Hemostatic belongs to the group of hemostatic agents - hemocoagulants, the mechanism of action of which is aimed at accelerating blood clotting. Depending on the type of drug, it can reduce the blood flow to the affected area or increase the activity of thrombus formation in general.

Hemocoagulants can be used both to affect the entire body, and locally. Next, consider the most common hemostatics for topical use.



The invention of hemostatics was the result of scientific progress, the beginning of which can be called the discovery of platelets by the French biologist G. Hayem in 1883. In 1916, the first anti-clotting agent, heparin, was discovered. In 1931, a Canadian veterinarian accidentally discovered a second substance, warfarin, an indirect anticoagulant. The main physiological anticoagulant, protein C, was discovered and described in 1976. Thanks to the consistent discovery and description of the action of all three anticoagulants, scientists were able to begin the development of new hemostatic agents.

Modern hemostatics are made on the basis of chitosan - an amino sugar, which is extracted from chitin contained in the shells of crustaceans or insects, as well as fungal cells of the Zygomycote department.


Despite the growing experience in the practical use of these drugs, there is no consensus on the mechanism that provides the hemostatic effect of chitosan, as well as understanding the physicochemical properties of this biopolymer, which determine its ability to stop bleeding. As a result, there are no unified approaches and standards for quality control of chitosan raw materials and finished local hemostatic agents derived from it.

Celox. Manufacturer MedTrade Products Ltd., UK


Celox hemostatics are used only with external bleeding or wounds of the limbs. This is due to the mechanism of fluid absorption, since when wounded in the chest or abdomen, the drug will glue everything inside, which will aggravate the condition of the victim. With open head injuries, Celox should also not be used.

Available in several variations depending on the task:

Granules. Celox in its pure form, packaged in packs of 2, 15 and 35 grams. Accordingly, 2 grams for capillary and small arterial bleeding (deep cuts or finger tears). The most common and popular variation is 15 grams. In combination with a tourniquet or tourniquet, it can stop bleeding in the event of a hand or foot tear, as well as a bullet or cut wound. 35 grams is the heavy artillery needed for a complete cut off of the shoulder or thigh. It must be remembered that the effect of the drug is not instantaneous, and the victim continues to lose blood if a tourniquet is not used.


Bandage or Z-folded bandage. Expensive, but universal tool, suitable for doctors and military medics. Viscose material is impregnated with granules and allows you to stop all types of external bleeding. In addition to being easy to use for tamponade, it is not afraid of rain or strong winds, which cannot be said about the powdered version.


Applicator. A means to stop bleeding in complex penetrating wounds. Due to its length and shape, the applicator allows you to deliver the granules directly to the source of bleeding. Despite the shape of the applicator, the granules from it can be used in the same way as the granules from the package.


Celox's chitosan is derived from shellfish shells, which can be a very unpleasant surprise for those who are allergic to seafood.

All Celox preparations are designed for one-time use, and they must not be stored open, as they lose their properties.

"Hemoflex". Producer LLC "Inmed", Russia


Hemoflex is a Z-folded bandage impregnated with a second generation hemostatic (some first generation drugs caused burns) with bactericidal properties, which can be left in the wound for up to 48 hours without side effects.


Chitosan "Hemoflex" - of plant origin, that is, from mushrooms. The bandage is very easily modeled according to the shape of the wound and has an excellent hemostatic effect.

I consider it most important to point out that "Hemoflex" can be used for wounds in the chest, abdomen or head.

"Means hemostatic sterile Gepoglos in granules". Producer LLC "Lumi", Russia


Available in several variations depending on the task:

Granules. "Gepoglos" in its pure form, packaged in packages of 15 and 35 grams. The functionality is similar to Celox pellets.


Z-folded bandage impregnated with hemostatic. The functionality is similar to the bandage from Hemoflex. Available in the form factor 8x100 cm and 8x150 cm.


In addition to the products listed above, the company produces hemostatic wipes for domestic use, hemostatic rubber tourniquets and immobilization splints in three sizes (for fingers 46x96x5 mm; standard 110x910x5 mm; XL 150x910x5 mm).

"Hemostatic dressing, antimicrobial "Hemospas BIO" sterile." Producer "MDK-MEDIKA", Russia


The company offers several generations of hemostatics, including the first, which generates heat during operation.

Execution options are very diverse:

Granules in packages of 5, 10, 15, 20 and 35 grams. The functionality is similar to the pellets from Celox and Gepoglos.


Bandage non-woven and Z-folded with double-sided granule application. Release forms: 7,5x150 cm, 8x150 cm, 7,5x300 cm and 8x300 cm in Z-fold form in individual bags and 7,5x300 cm and 8x300 cm in rolls in individual bags. Antimicrobial action is provided by the presence of iodopovidone. Has a rapid bactericidal effect on gram-positive and gram-negative bacteria.


Conclusions


First of all, you need to understand that the hemostatics of our manufacturers are very different from foreign ones and not for the worse, and some for the better.

St. Petersburg State University of Chemistry and Pharmacy, together with the Moscow Institute of Physics and Technology, conducted an interesting comparison of some hemostatics, which can be found Article, where there are a lot of scientific words, but for the layman everything is generally clear and there is even a rating.

Our manufacturer's lack of an applicator and the large selection of plain or Z-folded bandages hints that a well-done tamponade can do just fine without any plastic tubing. One side. On the other hand, it seems to me that it is not always possible to reach the source deep, for example, in the thigh. In any case, there is only one unequivocal conclusion - in addition to theoretical knowledge, you need to learn how to use all these tools. In the case of bandages, it is not necessary to spend an expensive tool for this.

Guidelines for tamponade with a regular bandage abound on the Internet, and raw pork knuckle is excellent as a patient. The main thing to remember is that medical tamponade of the wound is in no way connected with a gynecological agent.
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  1. +1
    7 October 2022 05: 22
    The main thing to remember is that medical tamponade of the wound is in no way connected with a gynecological agent.

    Apotheosis of this opus. wassat
    1. +4
      7 October 2022 06: 02
      Great and much needed article!
      Celox comes from the shells of shellfish, which can be a very unpleasant surprise for those who are allergic to seafood.

      Celox hemostatics are used only for external bleeding or injuries of the limbs.

      (some first generation drugs caused burns)



      An excellent article directly related to military affairs, informing about important points, but you only remember the last words, sorry.
      1. +1
        7 October 2022 06: 08
        An excellent article directly related to military affairs, informing about important points

        Who is treated according to the medical reference book, risks dying from a typo
        (Christian Friedrich Goebbel)
        1. +5
          7 October 2022 06: 13
          Quote: Amateur
          Who is treated according to the medical reference book, risks dying from a typo

          I do not need a guide to determine if there is bleeding or not. And knowledge is not superfluous, especially in such a case.
          1. +4
            7 October 2022 07: 02
            I don't need a guide identify whether there is bleeding or not.

            So "determine" or "stop"? To define the directory it is really not necessary. Stopping it is another matter entirely.
            ps In order to change the current gasket in the faucet, most people call plumbers. Your TV is repaired only by specialists.
            But the knowledge of medicine, "sufficient" for self-treatment, have a lot of people. Up to death.
            1. +2
              7 October 2022 07: 11
              Quote: Amateur
              So "determine" or "stop"? To define the directory it is really not necessary. Stopping it is another matter entirely.

              Well, if you need a guide so that you don’t inadvertently put a tourniquet around your neck, then oh.
              Quote: Amateur
              But the knowledge of medicine, "sufficient" for self-treatment, have a lot of people. Up to death.
              Stopping bleeding is not a cure! This is emergency help, and often self-help.
              So let's not silly verbiage about plumbers.
              1. +3
                7 October 2022 11: 18
                Well, if you need a guide so that you don’t inadvertently put a tourniquet around your neck, then oh.

                As a suffocator:

                Stopping bleeding is not a cure! This is emergency help, and often self-help.

                This does not change the fact that emergency care needs to be trained.
                1. +1
                  7 October 2022 11: 31
                  Quote from SincerityX
                  As a suffocator:

                  I'll blow my mind laughing it's more of a pressure bandage. hi And, which is noticeable, not around the throat.
                  1. +2
                    7 October 2022 12: 52
                    I'll blow my mind laughing it's more of a pressure bandage. hi And, which is noticeable, not around the throat.

                    I admit it's a good point.) hi
        2. +1
          8 October 2022 18: 47
          About women's pads - they are indispensable for extensive abrasions, and have been tested for decades in cycling and motorcycle sports. When the skin is scratched and bleeding on a fair area, the pads and over the adhesive tape allow you to leave the forest or where you fell and get to more medical aid. Since otherwise the friction of clothes on the wound will cause even more harm.
          It is better to have at least some knowledge of self-help than none.
          That's what upset me - the green-spotted packaging of the Russian bandage. If dropped into the weeds - look a little longer. It would be orange, so that it is immediately clear that this is a medical device!
      2. +1
        7 October 2022 09: 25
        Quote: Vladimir_2U
        Great and much needed article!

        You don’t need to read articles, but simply take a course, possibly paid, possibly within the framework of your enterprise, organized even by a trade union organization, under the guidance of professional paramedics of the SMP with training in manipulation. Theoretical literary reading is useless, and sometimes even harmful, because it creates the illusion of knowledge, which leads to erroneous decisions and actions.
        1. +3
          7 October 2022 10: 30
          Tell me, what is the harm in such knowledge?
          The chitosan for Celox comes from shellfish shells, which can become a very unpleasant surprise for those who are allergic to seafood.

          It must be remembered that the effect of the drug is not instantaneous, and the victim continues to bleed unless a tourniquet is used.

          The company offers several generations of hemostatics, including the first, which generates heat during operation.


          Quote: Hagen
          but simply to take a course, perhaps paid, perhaps within the framework of one's own enterprise, organized even by a trade union organization, under the guidance of professional paramedics of the SMP with training in manipulation.
          The wish is certainly cool, except for jokes, but in my conditions it is difficult to implement.
          Plus, are you confident in the quality of the knowledge taught there? And then, after all, the massive use of Esmarch's harnesses instead of turnstiles, as it were, hints that it is not ...
          1. +2
            7 October 2022 11: 23
            And then, after all, the massive use of Esmarch's harnesses instead of turnstiles, as it were, hints that it is not ...

            In fact, there is an opinion that the esmarch is safer when applied, but it’s another task to impose it on yourself, so you need to have an esmarch to help a friend and a turnstile (in fact, a woven tourniquet of the Red Army sounds better IMHO), for emergency self-help on the time of the battle, after which immediately, as it becomes possible to impose an esmarch.
            1. 0
              7 October 2022 11: 33
              Quote from SincerityX
              In fact, there is an opinion that esmarch is safer when applied

              Razvedos and involved doctors strongly disagree. Not to mention the speed and quality of imposition by inexperienced fighters.
          2. +2
            7 October 2022 11: 49
            Quote: Vladimir_2U
            Tell me, what is the harm in such knowledge?

            If you are a professional doctor, then nothing. And if you are just a passerby accountant (without pretensions to the profession), then by undertaking to resuscitate the victim after reading the article within the next three to four months, you will most likely make his death inevitable.
            Quote: Vladimir_2U
            Plus, are you confident in the quality of the knowledge taught there?

            The knowledge and skills of people who earn money by carrying out emergency activities at the scene of an accident are in every way deeper and more solid than that of a non-medical worker who comes to the scene of an accident by chance once in a lifetime.
            1. 0
              7 October 2022 12: 58
              And if you are just a passer-by accountant (without claiming to the profession), then by undertaking to resuscitate the victim after reading the article within the next three to four months, you will most likely make his death inevitable.

              That is, in your opinion, failure to provide assistance at all will not make his death inevitable, so what happens?
              The knowledge and skills of people who earn money by carrying out emergency activities at the scene of an accident are in every way deeper and more solid than that of a non-medical worker who comes to the scene of an accident by chance once in a lifetime.
              Of course, but the most important thing is experience, and experience is knowledge + skills + practice. However, nothing prevents you from learning and in the event that a medical worker is out of reach, this will help save a person’s life.
              With arterial bleeding, a person dies in a few minutes. You simply will not have time to look for a doctor.
            2. +1
              7 October 2022 13: 42
              Quote: Hagen
              And if you are just a passer-by accountant (without claiming to the profession), then by undertaking to resuscitate the victim after reading the article within the next three to four months, you will most likely make his death inevitable.

              Here you are confusing emergency care, and stopping bleeding is emergency care, with resuscitation!
              Quote: Hagen
              The knowledge and skills of people who earn money by carrying out emergency activities at the scene of an accident are in every way deeper and more solid than that of a non-medical worker who comes to the scene of an accident by chance once in a lifetime.
              Here I agree, but self-education is a necessary thing! Personally, I actually saved a thumping citizen, having managed to turn him over on his side when he began to vomit, but where did the knowledge come from? I read in a quick guide about the provision of emergency assistance.
  2. +1
    7 October 2022 12: 11
    Quote: Hagen
    And if you are just a passer-by accountant (without claiming to the profession), then by undertaking to resuscitate the victim after reading the article within the next three to four months, you will most likely make his death inevitable.

    If a situation arose when a passer-by accountant had to resuscitate the victim, then the victim initially had about zero chances of surviving. Stupidly because the victim is already dying (otherwise why resuscitation) and there is no qualified medical care nearby. And then he either tried to help as best he could, or watched the person die.
  3. 0
    7 October 2022 13: 01
    Strictly speaking, the basics of first aid should be taught at school (in the form of a course of a certain volume), and in some volumes in kindergarten (in the form of stories for children about what to do if you get hurt). With all the feeling of evidence of this knowledge, in the philistine environment they are NOT unified or systemic, and often even generally available to a particular person. This is not even a question of some kind of pre-war training - it is a question of improving the quality and safety of life. The ability to identify symptoms of dangerous conditions in oneself and loved ones and provide primary medical care is never superfluous.
    If you own a car, you at least in general terms know how it works - it should also be with physiology.
    1. 0
      7 October 2022 13: 47
      it’s taught there in a certain way, it’s a matter of legislation ... if you see a wounded man and help him and it turns out that he will suffer, for example, they did an indirect massage and broke a rib, then that’s it .. turma .. there are a lot of jambs in the legislation such as, for example, the law on edged weapons
      1. -1
        7 October 2022 14: 00
        Then okay - with an emphasis on helping yourself. There are many situations in which a person can find themselves without these skills and not survive. Stopping venous and arterial bleeding, applying splints, dressings, determining blood loss, actions in case of heart problems, etc.
        According to the law, yes, this is a really complicated issue from the point of view of law.
        1. 0
          7 October 2022 14: 19
          we need an integrated approach ... and teach from schools to provide assistance so as not to retrain in the army, and change car first-aid kits to sane ones and change the law .. one without the other will be ineffective ... let's say an accident ... arterial bleeding ... a first-aid kit can be do not open .. there is a miserable venous tourniquet, which supposedly stops the arterial one ...
        2. 0
          8 October 2022 18: 57
          about legislation, yes, this is a really difficult question from the point of view of law

          There are no restrictions on self-help. They can put you in jail for helping another person if he dies, and they will prove that from your hand-ass, and not from the wound itself. Theoretically, they can imprison a doctor for failing to provide assistance, but such episodes are not known to me.
  4. AB
    +1
    7 October 2022 16: 46
    medical tamponade of the wound is in no way connected with a gynecological remedy

    Well, well, tell me more. Only now the wife says that Tampaksy in pharmacies are gone. The explanation in pharmacies is simple - everything is to the front, everything is for victory ...
    1. +1
      7 October 2022 22: 04
      Explanation in pharmacies give a simple - all to the front

      doctors confirm that tampax can plug wounds.
      in fact, it is a TIGHTLY rolled piece of gauze, which is intended for tamponade.
      only the tail-rope must be removed from the wound - so that later you do not forget it there, on top of other bandages during the subsequent operation and dressing
    2. 0
      8 October 2022 18: 54
      Gaskets have some impregnations, from which they dry to the wound weaker than a bandage. Therefore, in cycling, "dailies" are carried with them. They are sold everywhere, cheap. If you fell and peeled off the skin, wash the abrasion, how much water is enough in the flask, and cover with gaskets. Fasten over with ordinary adhesive tape, and you can somehow screw it to the house, or the pharmacy, or in general somewhere from the road or from the forest.
      The pads are sterile and packed one at a time, and the packaging can be opened with one hand if the other is injured. The film from the packing of gaskets is waterproof, and it can be wrapped over if it falls in the rain.
      The important point is "extreme medicine", not conventional medicine.
      Clothes soaked in blood from abrasion - become "oak" and tear apart the wound again. That is why the pads are wrapped with tape - it is slippery. But not that it is not tight, but very loose. If the arms and legs and everything else between them are shaved, then the healing is without a trace, if the hairy ones are pustules, scars, a strange skin color.
      1. 0
        8 October 2022 23: 33
        There are no special impregnations.
        As in diapers, there is a hydrogel inside.
        Synthetic fiber that absorbs liquid 300-400 times its own dry weight.
        Therefore, there is no crust of the wound-bandage.
        And mobilized pads are issued for use as additional insoles, disposable.
    3. 0
      8 October 2022 23: 28
      Quote: AB
      medical tamponade of the wound is in no way connected with a gynecological remedy

      Well, well, tell me more. Only now the wife says that Tampaksy in pharmacies are gone. The explanation in pharmacies is simple - everything is to the front, everything is for victory ...

      Today I was in Magnit Cosmetic - a shaft, of all stripes, colors and calibers. My wife bought herself ...
      In pharmacies, I asked now, she said that it is much more expensive
  5. 0
    8 October 2022 10: 21
    I thank the author for a very interesting article on a topic that I knew nothing about. hi
  6. 0
    8 October 2022 23: 20
    It all looks like dietary supplements, they have been known about for 150 years, but they have never been used much, and here you definitely need this bag for 2000.
  7. 0
    21 October 2022 12: 30
    Better to have and not need than to need and not have!
    This also applies to honey. means and theoretical knowledge and, of course, the practice of using these same means.